Reaper removes physical immunities for melee characters, alternatively you can use Pride (Conc aura) to increase your damage or BOTD War Pike. Ondal gives 5% more experience.
Barb can wear (and dual wield) 2-handed swords such as BOTD, Grief or Last Wish Colossus in one hand. Sorc can use staves for extra skill bonuses (Memory or CTA Archon Staff).
2H white weapons have up to 6 sockets, unique weapons roll up to 3 sockets (Tomb Reaver), set/rare 2 soc (Immortal King).